Ballian N, Mantoudis E, Kaltsas GA.

Arch Gynecol Obstet. 2006 Mar;273(6):384-6. Epub 2005 Sep 30.

Renal Transplant Unit, Laiko Hospital, 17 Agiou Thoma street, Athens, 11527, Greece.



We report a woman with a history of polycystic ovary syndrome (PCOS) and nine first-trimester miscarriages following ovulation induction and in vitro fertilization. The majority of these attempts were associated with ovarian hyperstimulation syndrome. No causes of recurrent miscarriages other than PCOS were found. Following laparoscopic ovarian drilling (LOD) she delivered a live neonate at 30 weeks of gestation.


This case describes the difficulties associated with the management of patients with PCOS and recurrent abortions. We believe that LOD has helped prevent miscarriage in this patient. The early application of this technique in such patients needs to be formally assessed by a prospective study.

PMID: 16195901 [PubMed – indexed for MEDLINE]